Ability of a new oral nicotine substitute to reduce smoking urge in moderate smokers.
Addict Behav
; 31(3): 537-43, 2006 Mar.
Article
em En
| MEDLINE
| ID: mdl-15964703
ABSTRACT
The aim of this study was to assess the effectiveness of a new nicotine lozenge ( Nicopass 1.5 mg) in reducing smoking urge after an overnight abstinence. Twenty-four moderate smokers participated in a randomized, double-blind, placebo-controlled, 2-period crossover trial. The results showed that 1.5 mg-nicotine lozenge is superior to placebo in reducing smoking urge (p = 0.0001). In addition, nicotine lozenge, but not placebo, significantly improved vigilance and psychomotor performances (p < 0.05) and displayed a cardiac chronotropic effect. Thus, the 1.5-mg nicotine lozenge appears as an effective aid to alleviate acute tobacco withdrawal symptoms in moderate smokers.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome de Abstinência a Substâncias
/
Fumar
/
Abandono do Hábito de Fumar
/
Agonistas Nicotínicos
/
Nicotina
Tipo de estudo:
Clinical_trials
/
Etiology_studies
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Addict Behav
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
França