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Presurgical curettage appropriately reduces the number of Mohs stages by better delineating the subclinical extensions of tumor margins.
Chung, Vinh Q; Bernardo, Leo; Jiang, S Brian.
Afiliação
  • Chung VQ; Dermatology Surgery Unit, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Dermatol Surg ; 31(9 Pt 1): 1094-9; discussion 1100, 2005 Sep.
Article em En | MEDLINE | ID: mdl-16164856
BACKGROUND: Whether presurgical curettage (PC), light curettage performed before Mohs surgery to delineate tumor margin, is appropriate or causes unnecessary removal of normal tissue has not been well established. OBJECTIVE: We aim to determine histologically whether PC appropriately increases the size of the stage I specimen or causes unnecessary removal of healthy tissue. METHODS: Before a surgical margin guided by PC was taken, a hypothetical margin determined by visual and tactile assessment alone (no curettage [NC]) was marked outside the clinically defined tumor. Histologic analysis at the NC and the PC margins revealed whether the increase in the stage I specimen as a result of PC was appropriate. RESULTS: PC appropriately increased the stage I specimen in 21 cases and unnecessarily removed normal tissue in only 1 case. The estimation of tumor margins with PC was 15 times more accurate than with NC (p value = .0012). CONCLUSION: For basal cell and squamous cell carcinomas at least 4 mm in diameter, light curettage performed prior to Mohs surgery could better delineate subclinical extensions of the tumor margin and appropriately increase the size of the stage I specimen.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Carcinoma Basocelular / Carcinoma de Células Escamosas / Curetagem Tipo de estudo: Observational_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Dermatol Surg Assunto da revista: DERMATOLOGIA Ano de publicação: 2005 Tipo de documento: Article País de afiliação: Estados Unidos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Carcinoma Basocelular / Carcinoma de Células Escamosas / Curetagem Tipo de estudo: Observational_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Dermatol Surg Assunto da revista: DERMATOLOGIA Ano de publicação: 2005 Tipo de documento: Article País de afiliação: Estados Unidos