Experimental hyperthyroidism-induced oxidative stress and impairment of antioxidant defence system in rat testis.
Indian J Exp Biol
; 43(11): 1058-67, 2005 Nov.
Article
em En
| MEDLINE
| ID: mdl-16313068
ABSTRACT
Short-term hyperthyroidism, induced by daily administration of T3 (20 microg/100g body weight) for one, three, and five days consecutively, modulates oxidative stress and antioxidant defence parameters in mitochondrial and postmitochondrial fractions of testis in adult rats. Alteration in antioxidant defences along with oxidative stress parameters in testis by thyroid hormone was found to be associated with a decline in the number of sperms and disturbances in histoarchitecture of seminiferous tubules in the testes; the results indicated that induced hyperthyroid state altered testicular physiology by influencing antioxidant defence system of testes.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Testículo
/
Estresse Oxidativo
/
Hipertireoidismo
/
Antioxidantes
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Indian J Exp Biol
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Índia