Usefulness of an early neurofunctional assessment in predicting neurodevelopmental outcome in very low birthweight infants.
Arch Dis Child Fetal Neonatal Ed
; 91(2): F111-7, 2006 Mar.
Article
em En
| MEDLINE
| ID: mdl-16492947
ABSTRACT
OBJECTIVE:
To evaluate whether early neurofunctional assessment may be useful in predicting neurodevelopmental outcome in children of very low birth weight (VLBW).DESIGN:
Observational longitudinal study. SETTINGS Northern Italy. PATIENTS A total of 250 VLBW children (129 boys, 121 girls) born consecutively 1996-1999. MAIN OUTCOMEMEASURES:
Neurodevelopment at 36 months of chronological age, classified in accordance with the classification of Tardieu and the International classification of functioning.RESULTS:
Of the infants exhibiting normal neurodevelopment (n = 183) or major dysfunction (n = 17) at 3 months of corrected age, 72% and 94% respectively did not change their score during the study. Minor dysfunctions at 3 months of corrected age were transient in 17 (34%) children. After adjustment for neonatal variables, neurodevelopment at 3 months of corrected age remained predictive of dysfunction at 36 months (odds ratio = 4.33, 95% confidence interval 2.05 to 9.12). If the results for the normal and minor dysfunction groups were pooled, the predictive qualities of the 3 month neurofunctional assessment were sensitivity 0.5, specificity 0.99, positive predictive value 0.94, negative predictive value 0.93.CONCLUSION:
Early neurofunctional evaluation may be useful in predicting later neurodevelopmental outcome in VLBW children.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Deficiências do Desenvolvimento
/
Recém-Nascido de muito Baixo Peso
Tipo de estudo:
Diagnostic_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Child, preschool
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Female
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Humans
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Infant
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Male
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Newborn
Idioma:
En
Revista:
Arch Dis Child Fetal Neonatal Ed
Assunto da revista:
PEDIATRIA
/
PERINATOLOGIA
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Itália