Dramatic etanercept-induced remission of relapsing febrile sciatic neuralgia related to p46l mutation of the tnfrsf1a gene.
Clin Rheumatol
; 26(9): 1535-6, 2007 Sep.
Article
em En
| MEDLINE
| ID: mdl-16941196
ABSTRACT
An adult patient experienced attacks of severe low back pain and sciatic neuralgia for several years, sometimes associated with myalgias, skin lesions, and high fever. Specific inflammatory laboratory tests were the major abnormalities. P46L mutation in the gene on chromosome 12p13 that encodes tumor necrosis factor receptor superfamily 1A (TNFRSF1A) was found. Management with anti-TNF agent was effective with a complete remission of bouts of pain and fever.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ciática
/
Imunoglobulina G
/
Fator de Necrose Tumoral alfa
/
Receptores do Fator de Necrose Tumoral
/
Receptores Tipo I de Fatores de Necrose Tumoral
Limite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Clin Rheumatol
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
França