[Favourable results with surgical treatment in 43 children with hypoplastic left-heart syndrome or similar disorders, 1999-2005]. / Gunstige resultaten van chirurgische behandeling van 43 kinderen met het hypoplastisch linkerhartsyndroom of een equivalente afwijking, 1999/'05.
Ned Tijdschr Geneeskd
; 150(35): 1930-5, 2006 Sep 02.
Article
em Nl
| MEDLINE
| ID: mdl-16999278
ABSTRACT
OBJECTIVE:
To describe the results of surgical treatment of hypoplastic left-heart syndrome (HLHS) and HLHS-like disorders in the Amsterdam-Leiden Centre for Congenital Heart Disease, the Netherlands.DESIGN:
Retrospective, descriptive.METHOD:
Data were collected on 43 neonates with HLHS or similar disorders who underwent surgical treatment between December 1999 and December 2005. HLHS was present in 37 patients and 6 had disorders similar to HLHS (unbalanced atrioventricular septal defect, truncus arteriosus with hypoplastic left ventricle, double inlet left ventricle). Surgery was performed in 3steps:
Norwood operation shortly after birth (n = 43), bidirectional cavopulmonary anastomosis a few months later (n = 30) and total cavopulmonary connection at the age of 2-3 years (n = 10). During the Norwood operation, the first 21 patients received a modified Blalock shunt (between the right brachiocephalic artery and pulmonary artery), whereas the following 22 patients received a Sano shunt (between the right ventricle and pulmonary artery).RESULTS:
Of the 43 patients, 11 died 7 within 30 days of the first operation, 2 between the first and second operation, and 2 between the second and third operation. Actuarial survival for the entire group is 74% (32/43). The mortality rate was lower with the Sano shunt (9%; 2/22) than with the modified Blalock shunt (43%; 9/21). Catheter interventions were necessary in 10 patients 6 had balloon dilatation of the distal aortic arch and 4 had balloon dilatation/stent placement for narrowed pulmonary arteries. With a median follow-up of 22 months (range 1-75), 2 patients had marked neurological side effects. All 32 surviving patients were in good clinical condition.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome do Coração Esquerdo Hipoplásico
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Newborn
Idioma:
Nl
Revista:
Ned Tijdschr Geneeskd
Ano de publicação:
2006
Tipo de documento:
Article