Mitochondrial toxins and neurodegenerative diseases.
Front Biosci
; 12: 986-1007, 2007 Jan 01.
Article
em En
| MEDLINE
| ID: mdl-17127354
ABSTRACT
The selective loss of a particular subset of neurons is a common feature of neurodegenerative disorders. A failure in respiratory chain complex activities in mitochondria seems to be a causative factor. The aim of this review is to describe the most important toxins affecting the mitochondrial function, which could be involved in the incidence of some of these diseases MPTP, rotenone and 3-nitropropionic (3-NPA).
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Propionatos
/
Rotenona
/
Doenças Neurodegenerativas
/
Intoxicação por MPTP
/
Mitocôndrias
/
Nitrocompostos
Tipo de estudo:
Prognostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Front Biosci
Assunto da revista:
BIOLOGIA
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Espanha