Placental mesenchymal dysplasia.
Arch Pathol Lab Med
; 131(1): 131-7, 2007 Jan.
Article
em En
| MEDLINE
| ID: mdl-17227114
ABSTRACT
CONTEXT Placental mesenchymal dysplasia is characterized by placentomegaly and may be mistaken for molar pregnancy both clinically and macroscopically because of the presence of "grapelike vesicles." It may be associated with a completely normal fetus, a fetus with growth restriction, or a fetus with features of Beckwith-Wiedemann syndrome. OBJECTIVE:
To review the etiology, molecular pathology, gross and microscopic features, clinical presentation, complications, and differential diagnosis of placental mesenchymal dysplasia. DATA SOURCES The PubMed and the Medline databases were systematically searched for articles between 1970 and 2006. The following keywords were used placental mesenchymal dysplasia, mesenchymal hyperplasia, molar pregnancy, pseudomolar pregnancy, Beckwith-Wiedemann syndrome, and placentomegaly. Relevant references from review articles were also searched.CONCLUSIONS:
Placental mesenchymal dysplasia should be considered in the differential diagnosis when the ultrasonographic findings show a cystic placenta. Close attention should be paid to fetal morphology for early recognition of fetal complications and to prevent unnecessary termination of pregnancy in cases associated with a normal fetus.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças Placentárias
/
Placentação
/
Mesoderma
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Arch Pathol Lab Med
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Estados Unidos