Primitive neuroectodermal tumor of the central nervous system with glial differentiation: a FISH study of an adult case.
Clin Neuropathol
; 26(1): 12-6, 2007.
Article
em En
| MEDLINE
| ID: mdl-17290931
ABSTRACT
Primitive neuroectodermal tumors (PNETs) of the central nervous system (CNS), a rare occurrence in adults, may show glial differentiation and can be misinterpreted as pure astrocytic neoplasms. Few fluorescence in situ hybridization (FISH) studies have been carried out on these tumors; isochromosome 17q was found to be the major chromosomal abnormality. We present the case of an adult in which we performed a FISH study of both the glial and neuronal components. A complex array of FISH changes, not including an isochromosome 17q were identified.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Trissomia
/
Cromossomos Humanos Par 17
/
Neoplasias Encefálicas
/
Tumores Neuroectodérmicos Primitivos
Tipo de estudo:
Prognostic_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Clin Neuropathol
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Espanha