Anti-inflammatory effect of virgin olive oil in stable coronary disease patients: a randomized, crossover, controlled trial.
Eur J Clin Nutr
; 62(4): 570-4, 2008 Apr.
Article
em En
| MEDLINE
| ID: mdl-17375118
ABSTRACT
OBJECTIVES:
To assess the effect of two similar olive oils, but with differences in their phenolic compounds (powerful antioxidant compounds), on inflammatory markers in stable coronary heart disease patients.DESIGN:
Placebo-controlled, crossover, randomized trial.SETTING:
Cardiology Department of Hospital del Mar and Institut Municipal d'Investigació Mèdica (Barcelona).SUBJECTS:
Twenty-eight stable coronary heart disease patients.INTERVENTIONS:
A raw daily dose of 50 ml of virgin and refined olive oil (ROO) was sequentially administered over two periods of 3-weeks, preceded by 2-week washout periods in which ROO was used.RESULTS:
Interleukin-6 (P<0.002) and C-reactive protein (P=0.024) decreased after virgin olive oil intervention. No changes were observed in soluble intercellular and vascular adhesion molecules, glucose and lipid profile.CONCLUSIONS:
Consumption of virgin olive oil, could provide beneficial effects in stable coronary heart disease patients as an additional intervention to the pharmacological treatment.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Gorduras Insaturadas na Dieta
/
Óleos de Plantas
/
Proteína C-Reativa
/
Interleucina-6
/
Doença das Coronárias
/
Antioxidantes
Tipo de estudo:
Clinical_trials
Limite:
Aged
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Eur J Clin Nutr
Assunto da revista:
CIENCIAS DA NUTRICAO
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Espanha