Mammary adenocarcinoma in a young female hypercholesterolemic rat.
Jikken Dobutsu
; 40(4): 553-5, 1991 Oct.
Article
em En
| MEDLINE
| ID: mdl-1748175
ABSTRACT
Pathological examination of a 12-week-old female rat with hypercholesterolemia revealed mammary adenocarcinoma. Grossly, one grayish-white nodule was found in the hypoderm near the right posterior mammary gland. Histologically, the nodule was composed of variable-sized epithelial cells which lined the tubules and ducts in one to several layers, accompanied by proliferation of connective tissue in the stroma. Mitotic figures, necrosis and hemorrhage appeared frequently throughout the lesion. The tumor cells had invaded the surrounding muscular tissue.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças dos Roedores
/
Adenocarcinoma
/
Neoplasias Mamárias Animais
/
Hipercolesterolemia
Limite:
Animals
Idioma:
En
Revista:
Jikken Dobutsu
Ano de publicação:
1991
Tipo de documento:
Article
País de afiliação:
Japão