Analysis of independent risk factors for death among pediatric patients with candidemia and a central venous catheter in place.
Infect Control Hosp Epidemiol
; 28(7): 799-804, 2007 Jul.
Article
em En
| MEDLINE
| ID: mdl-17564981
ABSTRACT
OBJECTIVE:
To use multivariate analysis to determine risk factors for death among pediatric patients with candidemia and a central venous catheter in place.DESIGN:
Retrospective cohort study conducted at Santa Casa Complexo Hospitalar, a 1,200-bed teaching hospital in southern Brazil.METHODS:
All cases of candidemia in pediatric patients (age,RESULTS:
A total of 61 patients were included in the study, including 14 neonates. Most (63.9%) of these patients were girls, and the median age was 0.3 years. A total of 80.3% of candidemia cases were due to species other than Candida albicans, primarily Candida parapsilosis (32.8% of cases) and Candida tropicalis (24.6% of cases). Using multivariate analysis, we demonstrated that failure to remove the central venous catheter was an independent risk factor for early death among pediatric patients with candidemia. However, patients whose catheters were retained were sicker than patients whose catheters were removed, and catheter removal had no impact on late death. Instead, severity of illness determined using the PRISM III score was also an independent predictor of late death.CONCLUSIONS:
Results from this study suggest that systematic removal of catheters from pediatric patients with candidemia does not reduce the occurrence of late death.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Candidíase
/
Cateterismo Venoso Central
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Newborn
Idioma:
En
Revista:
Infect Control Hosp Epidemiol
Assunto da revista:
DOENCAS TRANSMISSIVEIS
/
ENFERMAGEM
/
EPIDEMIOLOGIA
/
HOSPITAIS
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Reino Unido