[The effect of hypothermia on the wavelength and vulnarability to ventricular arrhythmias in mammals].
Ross Fiziol Zh Im I M Sechenova
; 93(3): 289-99, 2007 Mar.
Article
em Ru
| MEDLINE
| ID: mdl-17598472
ABSTRACT
Arrhythmias developing in isolated Langendorff-perfused heart following the cooling of the perfusion solution from +37 to +3 degrees C were studied in rats and winter hibernating ground squirrels Citellus undulatus with application of no drugs. In rats, hypothermia significantly increased the probability of ventricular arrhythmias (from 22 +/- 6 % at 37 degrees C to 56 +/- 14 % at 17 degrees C). Excitation failure was observed in the rat hearts below 10 +/- 1 degrees C. The appearance of arrhythmias was closely correlated with a decrease in the wavelength which strongly suggests a reentrant mechanism of the hypothermic arrhythmias. In contrast, ground squirrels showed insensibility of the wavelength to cooling and were resistant to arrhythmias during hypothermia.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Arritmias Cardíacas
/
Sciuridae
/
Hibernação
/
Hipotermia
Limite:
Animals
Idioma:
Ru
Revista:
Ross Fiziol Zh Im I M Sechenova
Assunto da revista:
FISIOLOGIA
Ano de publicação:
2007
Tipo de documento:
Article