Accelerated regeneration of trypsin-treated surface antigens of simian virus 40-transformed BALB/3T3 cells induced by X-irradiation.
Cancer Res
; 36(4): 1258-62, 1976 Apr.
Article
em En
| MEDLINE
| ID: mdl-177205
ABSTRACT
The antigens of SV40-transformed BALB/3T3 cells measured by a radioisotopic footpad assay after removal by trypsin treatment regenerated in vitro in 3 to 6 hr. After X-irradiation with 3000 R, however, the antigens were regenerated to normal levels within 1 h. X-ray doses of between 1000 and 5000 R accelerated the regeneration of cell surface antigens, while X-irradiation with the larger dose of 8000 R did not. X-irradiation of nontrypsinized tumor cells was without effect. Possible mechanisms of this phenomenon are discussed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Efeitos da Radiação
/
Transformação Celular Neoplásica
/
Vírus 40 dos Símios
/
Antígenos Virais
Tipo de estudo:
Etiology_studies
Limite:
Animals
Idioma:
En
Revista:
Cancer Res
Ano de publicação:
1976
Tipo de documento:
Article