[Serum proteomics study of chronic gastritis with dampness syndrome in traditional Chinese medicine].
Zhong Xi Yi Jie He Xue Bao
; 5(5): 514-6, 2007 Sep.
Article
em Zh
| MEDLINE
| ID: mdl-17854551
ABSTRACT
OBJECTIVE:
To explore microcosmic information in chronic gastritis dampness syndrome by using serum proteomics of patients with chronic gastritis dampness syndrome.METHODS:
Serum proteomics of 18 dampness syndrome cases, 17 non-dampness syndrome cases in chronic gastritis patients and 8 normal controls were analyzed by surface enhanced laser desorption/ionization-time of flight (SELDI-TOF) protein-chip.RESULTS:
There was a high expression trend in three ratios of charge (of an electron) to mass (M/S) of 3.2 kD, 6.4 kD and 8.1 kD of protein expression spectrum from patients with chronic gastritis dampness syndrome, and the wave peak value was over 10 units. There was a low expression trend in above-mentioned sites of protein expression spectrum from patients with chronic gastritis non-dampness syndrome and normal group. The wave peak value of patients with chronic gastritis non-dampness syndrome was about or below 10 units, and the wave peak value in normal group was below 5 units.CONCLUSION:
There exists a certain significance to explore biologic theory basis of chronic gastritis dampness syndrome by analyzing the serum proteomics.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas Sanguíneas
/
Proteômica
/
Gastrite
/
Medicina Tradicional Chinesa
Tipo de estudo:
Diagnostic_studies
Limite:
Female
/
Humans
/
Male
Idioma:
Zh
Revista:
Zhong Xi Yi Jie He Xue Bao
Assunto da revista:
MEDICINA
/
TERAPIAS COMPLEMENTARES
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
China