Identification of fetal problems associated with anticonvulsant usage and maternal epilepsy.
Obstet Gynecol Clin North Am
; 18(4): 933-51, 1991 Dec.
Article
em En
| MEDLINE
| ID: mdl-1803310
ABSTRACT
This article reviews the general approach for assessing teratogenic risks related to fetal exposure, concentrating on the specific patterns associated with anticonvulsant usage and maternal epilepsy. Major anomalies that might be detected prenatally are presented, as well as the patterns of minor anomalies (syndromes) that might be detected at birth or later. Each of the specific drugs used in the treatment of epilepsy is reviewed in detail. In addition, recent information concerning genetically determined variations in the metabolism of antiepileptic drugs is discussed in light of how genetic factors might relate to teratogenicity.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Complicações na Gravidez
/
Anormalidades Induzidas por Medicamentos
/
Ultrassonografia Pré-Natal
/
Epilepsia
/
Doenças Fetais
/
Anticonvulsivantes
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Obstet Gynecol Clin North Am
Assunto da revista:
GINECOLOGIA
/
OBSTETRICIA
Ano de publicação:
1991
Tipo de documento:
Article