Synchronous primary gastric mantle cell lymphoma and early gastric carcinoma: a case report.
Pathol Res Pract
; 204(6): 407-11, 2008.
Article
em En
| MEDLINE
| ID: mdl-18282664
ABSTRACT
Mantle cell lymphoma (MCL) commonly invades the gastrointestinal (GI) tract. However, primary GI MCL is rare. We experienced a case of synchronous early gastric cancer (EGC) with primary gastric MCL found as a single early lesion rather than as multiple lymphomatous polyposis. An EGC was found in the cardia of a 64-year-old male on a routine GI endoscopic examination. A specimen obtained by total gastrectomy revealed another slightly elevated lesion in the pylorus. Microscopically, monotonous small- to medium-sized atypical lymphocytes with angulated nuclei formed a mass beneath the gastric mucosa. On immunohistochemical staining, the tumor cells revealed strong positivity for cyclin D1, positivity for both CD20 and bcl-2, and weak positivity for CD5, suggesting MCL. Clinically, there was no lymphoma in any other part of the body. This is the first case of an EGC accompanying a primary gastric MCL. Further investigation of a relationship between MCL and EGC and of factors that may affect GI involvement of MCL is necessary.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Gástricas
/
Adenocarcinoma
/
Linfoma de Célula do Manto
/
Neoplasias Primárias Múltiplas
Limite:
Humans
/
Male
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Middle aged
Idioma:
En
Revista:
Pathol Res Pract
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Coréia do Sul