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[Extracorporeal circulation and hypothermy surgery in tumors with vena cava extension: 20 years experience at the University Clinic of Navarra]. / Cirugía con circulación extracorpórea e hipotermia en tumores con extensión a vena cava: 20 años de experiencia de la clínica Universitaria de Navarra.
Rioja Zuazu, J; Rodríguez-Rubio Cortadillas, F; Zudaire Bergera, J J; Saiz Sansi, A; Rosell Costa, D; Robles García, J E; Rábago, G; Berián Polo, J M.
Afiliação
  • Rioja Zuazu J; Departamento de Urología, Clínica Universitaria, Universidad de Navarra, Pamplona. jriojazu@gmail.nl
Actas Urol Esp ; 32(4): 396-405, 2008 Apr.
Article em Es | MEDLINE | ID: mdl-18540260
ABSTRACT

OBJECTIVE:

We present our 20 years experience treating patients with vena cava extension in whom an extracorporeal circulation, hypothermia, cardio circulatory arrest (ECC-H-CCA) in order to perform, together with a tumoral resection, a thrombus resection. MATERIAL AND

METHODS:

From 1985 to 2005 a total of 28 retroperitoneal tumor were treated 25 renal cancers, a Wilms tumor, a paratesticular rabdomiosarcoma, and a pheocromocitoma. All of them had an extension by means of thrombus above the suprahepatics veins. All of them were treated by means of ECC-H-CCA for thrombus extraction. A descriptive study of the serie is performed as well as a Kaplan Meyer survival study.

RESULTS:

Surgical complications were present within 10 patients (35%), with a surgical mortality of two patients (7%) one intra-operatively because a massive embolism of the lungs and the other because of a lung embolism on the 4th post-operative day. Global actuarial survival was 29.1+/-10% at three years and 17.5+/-8% at five years. Analyzing only who do not have metastatic lesions, nor lymph nodes at diagnosis their three year survival was 50.9+/-16.3% and 32.2+/-16% at five years. Mean while those who have any metastatic lesion at diagnosis their three and five years survival was 20.8+/-12% and 10.4+/-9% respectively.

CONCLUSIONS:

The employ of surgical techniques with ECC-H-CCA with in oncological pathology associated with vena cava thrombus is justified and its employment does not worsen the survival; it is indicated because its results, allowing a complete tumoral resection in a safe and reproducible fashion.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Veia Cava Inferior / Circulação Extracorpórea / Hipotermia Induzida / Neoplasias Renais / Células Neoplásicas Circulantes Limite: Humans País/Região como assunto: Europa Idioma: Es Revista: Actas Urol Esp Ano de publicação: 2008 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Veia Cava Inferior / Circulação Extracorpórea / Hipotermia Induzida / Neoplasias Renais / Células Neoplásicas Circulantes Limite: Humans País/Região como assunto: Europa Idioma: Es Revista: Actas Urol Esp Ano de publicação: 2008 Tipo de documento: Article