Walking and inflammatory markers in individuals screened for type 2 diabetes.
Prev Med
; 47(4): 417-21, 2008 Oct.
Article
em En
| MEDLINE
| ID: mdl-18652841
ABSTRACT
OBJECTIVE:
To investigate the association of walking activity with inflammatory markers and fasting insulin in a bi-ethnic population screened for type 2 diabetes in Leicester, United Kingdom, between 2005 and 2006.METHOD:
Physical activity, adipocytokine, high-sensitivity C-reactive protein and fasting insulin measurements were available for 400 individuals screened for type 2 diabetes. Of the 400 participants, 56% were diagnosed with normal glucose control, 36% with prediabetes and 8% with diabetes.RESULTS:
Multivariate statistical analysis showed that those who reported walking for at least 30 min on at least 5 days/week had lower levels of C-reactive protein, interleukin-6, and tumor necrosis factor-alpha compared to those who reported lower walking activity levels, after adjustment for other modes of moderate-to-vigorous intensity physical activity, age, ethnicity, sex, social deprivation and smoking status. Further adjustment for waist circumference attenuated the association of walking with tumor necrosis factor-alpha.CONCLUSION:
Walking activity, independent of other forms of physical activity, is associated with lower levels of circulating pro-inflammatory markers.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteína C-Reativa
/
Caminhada
/
Interleucina-6
/
Fator de Necrose Tumoral alfa
/
Diabetes Mellitus Tipo 2
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
Prev Med
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Reino Unido