Environmental variation, fluctuating selection and genetic drift in subdivided populations.
Theor Popul Biol
; 74(3): 233-50, 2008 Nov.
Article
em En
| MEDLINE
| ID: mdl-18692081
ABSTRACT
Although there have many studies of the population genetical consequences of environmental variation, little is known about the combined effects of genetic drift and fluctuating selection in structured populations. Here we use diffusion theory to investigate the effects of temporally and spatially varying selection on a population of haploid individuals subdivided into a large number of demes. Using a perturbation method for processes with multiple time scales, we show that as the number of demes tends to infinity, the overall frequency converges to a diffusion process that is also the diffusion approximation for a finite, panmictic population subject to temporally fluctuating selection. We find that the coefficients of this process have a complicated dependence on deme size and migration rate, and that changes in these demographic parameters can determine both the balance between the dispersive and stabilizing effects of environmental variation and whether selection favors alleles with lower or higher fitness variance.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Seleção Genética
/
Deriva Genética
/
Genética Populacional
Tipo de estudo:
Health_economic_evaluation
Idioma:
En
Revista:
Theor Popul Biol
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Reino Unido