Diagnosis and surgical treatment of a Chiari I-like malformation in an African lion (Panthera leo).
J Zoo Wildl Med
; 39(3): 421-7, 2008 Sep.
Article
em En
| MEDLINE
| ID: mdl-18817006
ABSTRACT
A 13-mo-old intact male African lion (Panthera leo) presented with a 3-mo history of lethargy, ventral flexion of the neck, abnormal vocalization, and ataxia. Hemogram and serum biochemistries were within normal limits except for the presence of hypokalemia (2.7 mEq/L) and hypochloridemia (108 mEq/L). When no improvement was noted with oral potassium gluconate supplementation, a computed tomography scan of the brain and skull was performed, and no abnormalities were noted. However, magnetic resonance imaging detected occipital bone thickening, crowding of the caudal cranial fossa with cerebellar compression and herniation, and cervical syringohydromyelia, which was consistent with a Chiari I-like malformation. Foramen magnum decompression was performed to relieve the compression of the cerebellum. The animal recovered well with subsequent resolution of clinical signs. Hypovitaminosis A has been proposed previously as the underlying etiology for this malformation in lions with similar clinical presentations. This lion's serum and liver vitamin A concentrations were low (100 ng/ml and 25.31 microg/g, respectively) compared to concentrations reported for domestic carnivores and support hypovitaminosis A as the underlying cause of this animal's Chiari I-like malformation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Malformação de Arnold-Chiari
/
Deficiência de Vitamina A
/
Descompressão Cirúrgica
/
Leões
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Animals
Idioma:
En
Revista:
J Zoo Wildl Med
Assunto da revista:
MEDICINA VETERINARIA
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Estados Unidos