Measurement of human trabecular bone by novel ultrasonic bone densitometry based on fast and slow waves.
Osteoporos Int
; 20(7): 1215-24, 2009 Jul.
Article
em En
| MEDLINE
| ID: mdl-18989720
ABSTRACT
SUMMARY:
Two longitudinal transmitted waves, fast and slow waves, were observed by employing a new quantitative ultrasound (QUS) method. The trabecular bone measurements generated by this method reflect three-dimensional structural information, and the new QUS parameters were able to identify vertebral fractures.INTRODUCTION:
The aims were to identify new quantitative ultrasound (QUS) parameters that based on new QUS method reflecting not only bone volume but also the microstructures of trabecular bone ex vivo and to observe how much they predict fracture risk in vivo.METHODS:
Ex vivo measurement Three human femoral heads were used for the experiment. Attenuation of the slow wave, attenuation of the fast wave, speed of the slow wave, speed of the fast wave (SOFW), bone mass density of trabecular bone, and elastic modulus of the trabecular bone (EMTb) of each specimen were obtained using a new QUS method and compared with three-dimensional structural parameters measured by micro-computed tomography. In vivo measurement Eighty-nine volunteers were enrolled, and the bone status in the distal radius was measured using a new QUS method. These parameters were compared with data evaluated by peripheral quantitative computed tomography and dual X-ray absorptiometry.RESULTS:
Ex vivo measurement SOFW and EMTb showed correlations with the parameter of trabecular anisotropy. In vivo measurement The new QUS parameters were able to identify vertebral fractures.CONCLUSION:
The newly developed QUS technique reflects the three-dimensional structure and is a promising method to evaluate fracture risk.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Rádio (Anatomia)
/
Densidade Óssea
/
Cabeça do Fêmur
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Asia
Idioma:
En
Revista:
Osteoporos Int
Assunto da revista:
METABOLISMO
/
ORTOPEDIA
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Japão