The impact of radiotherapy on swallowing and speech in patients who undergo total laryngectomy.
Otolaryngol Head Neck Surg
; 139(6): 792-7, 2008 Dec.
Article
em En
| MEDLINE
| ID: mdl-19041505
ABSTRACT
OBJECTIVES:
Quality of life studies have shown no detrimental effect with radiotherapy (RT) in patients who have a total laryngectomy. We wished to determine the effect of RT (initial or postoperative) specifically on the swallowing and voice function in patients treated by total laryngectomy (TL) for carcinoma of the larynx.DESIGN:
Multicenter chart review.SETTING:
Multicenter study in the Greater Manchester and Lancashire area.PARTICIPANTS:
A total of 121 postlaryngectomy patients all of whom had completed definitive treatment at least 6 months before this study. Twenty-six patients had total laryngectomy as a single modality treatment and 95 had total laryngectomy and radiotherapy. MAIN OUTCOMEMEASURES:
Swallowing (solid food, soft diet or fluid/PEG) and voice development.RESULTS:
Swallowing was better in the group who had no radiotherapy (P = 0.0037). There was no difference in voice function between the two groups. We also demonstrated that females had a worse swallowing outcome (P = 0.0101), as did advanced nodal stage (P = 0.001).CONCLUSIONS:
RT adversely affects the swallowing results but not the speech results after TL when given either as initial treatment or postoperatively. This should be kept in mind in the decision-making process in the treatment of patients with carcinoma of the larynx.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Carcinoma de Células Escamosas
/
Transtornos de Deglutição
/
Distúrbios da Voz
/
Neoplasias Laríngeas
/
Laringectomia
Tipo de estudo:
Clinical_trials
/
Guideline
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
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Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Otolaryngol Head Neck Surg
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Reino Unido