[Conservative E(y)2/Sus1 protein interacts with the Su(Hw)-dependent insulators in Drosophila].
Genetika
; 45(3): 330-5, 2009 Mar.
Article
em Ru
| MEDLINE
| ID: mdl-19382683
ABSTRACT
Insulators are regulatory elements having two properties. First, they are able to disturb the interaction between promoters and enhancers/silencers. Second, they are able to block distribution of the heterochromatin. The best-studied are the Su(Hw)-dependent insulators of Drosophila melanogaster, activity of which is determined by the Su(Hw) protein. In this study it was demonstrated that novel, evolutionary conservative transcription factor E(y)2/Sus1 interacted with the Su(Hw) zinc-finger domain and was present in the protein complex, associated with the Su(Hw)-dependent insulators.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas Repressoras
/
Fatores de Transcrição
/
Heterocromatina
/
Proteínas de Drosophila
/
Elementos Isolantes
/
Complexos Multiproteicos
/
Proteínas de Ligação a DNA
Limite:
Animals
Idioma:
Ru
Revista:
Genetika
Ano de publicação:
2009
Tipo de documento:
Article