Genetic susceptibility to psoriasis: an emerging picture.
Genome Med
; 1(7): 72, 2009 Jul 22.
Article
em En
| MEDLINE
| ID: mdl-19638187
ABSTRACT
Psoriasis is recognized as a complex disease for which multiple genetic and non-genetic factors influence susceptibility. The major susceptibility locus resides in the MHC class I region and, until relatively recently, evidence for non-MHC loci was inconsistent. Like many common diseases, knowledge of the genetic basis of this condition has been advanced dramatically in recent times with the advent of genome-wide association studies using single nucleotide polymorphisms. Here, we give an overview of current knowledge of genetic risk factors for psoriasis and consider emerging studies that may further add to our understanding of the genetic basis of the disease.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Risk_factors_studies
Idioma:
En
Revista:
Genome Med
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Reino Unido