Adenovirus.
Curr Top Microbiol Immunol
; 343: 195-224, 2010.
Article
em En
| MEDLINE
| ID: mdl-20376613
ABSTRACT
Of the 53 different human adenovirus (HAdV) serotypes belonging to species A-G, a significant number are associated with acute respiratory, gastrointestinal and ocular infections. Replication-defective HAdV-5-based vectors also continue to play a significant role in gene transfer trials and in vaccine delivery efforts in the clinic. Although significant progress has been made from studies of AdV biology, we still have an incomplete understanding of AdV's structure as well as its multifactorial interactions with the host. Continuing efforts to improve knowledge in these areas, as discussed in this chapter, will be crucial for revealing the mechanisms of AdV pathogenesis and for allowing optimal use of AdV vectors for biomedical applications.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Adenoviridae
/
Internalização do Vírus
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Curr Top Microbiol Immunol
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Estados Unidos