Pd-catalyzed decarboxylative Heck vinylation of 2-nitrobenzoates in the presence of CuF2.
Beilstein J Org Chem
; 6: 43, 2010 May 03.
Article
em En
| MEDLINE
| ID: mdl-20563276
ABSTRACT
A new protocol for the decarboxylative Heck vinylation of benzoic acids is disclosed. In the presence of a catalyst system generated in situ from Pd(OAc)2 (2 mol %), CuF2 (2 equiv), and benzoquinone (0.5 equiv) in NMP, a wide range of olefins were coupled with various 2-nitrobenzoates at 130 ° C with the release of carbon dioxide to afford the corresponding vinyl arenes in good yields.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Beilstein J Org Chem
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Alemanha