[Brief treatment with thymopentin as adjuvant in vaccination for hepatitis B: controlled study in patients on periodic hemodialysis]. / Trattamento breve con timopentina come adiuvante nella vaccinazione anti-epatite B: studio controllato in pazienti sottoposti ad emodialisi periodica.
Riv Eur Sci Med Farmacol
; 12(2): 135-9, 1990 Apr.
Article
em It
| MEDLINE
| ID: mdl-2080311
ABSTRACT
Eleven hemodialysis patients (9 M, 2 F, aged 65 +/- 20 yrs) (Group A) were treated with thymopentin (TP-5) 50 mg as adjuvant therapy to HB vaccination, with 3 weekly administrations, the week before and the two following the first dose of Pasteur vaccine, 5 micrograms. The percentage of patients developing a sufficient antibody titer (20 mUI/ml) after 4 vaccine doses was not statistically different from that obtained among control groups B and C. The age- and sex- matched controls received the same vaccine schedule without adjuvant. The percentages were as follows Group A 54.5%, Group B 63.6%, Group C 60%. No local or systemic side effects were encountered after the TP-5 administration. The authors suggest that a short TP-5 treatment as an adjuvant therapy to HB vaccination is not effective in patients maintained on hemodialysis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Adjuvantes Imunológicos
/
Timopentina
/
Diálise Renal
/
Hepatite B
Limite:
Aged
/
Aged80
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
It
Revista:
Riv Eur Sci Med Farmacol
Ano de publicação:
1990
Tipo de documento:
Article