Statin therapy in lupus-mediated atherogenesis: two birds with one stone?
Ann Rheum Dis
; 70(2): 245-8, 2011 Feb.
Article
em En
| MEDLINE
| ID: mdl-21068103
ABSTRACT
The atherosclerotic process is accelerated in patients with systemic lupus erythematosus (SLE). In addition to a robust lipid-lowering effect, various immunomodulatory functions have been ascribed to statins. By virtue of the latter they may be able to reduce atherosclerotic vascular disease in SLE by inhibiting immune activation within the arterial wall and by attenuating lupus activity. The effects of statins on SLE as well as on lupus-mediated atherogenesis in vivo are discussed in this viewpoint.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Inibidores de Hidroximetilglutaril-CoA Redutases
/
Aterosclerose
/
Lúpus Eritematoso Sistêmico
Tipo de estudo:
Etiology_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Ann Rheum Dis
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Estados Unidos