[The photopic electroretinogram in normal adult sd rat].

ABSTRACT

PURPOSE: To study the characteristics of photopic flash electroretinogram (ERG) in normal adult SD rats. METHODS: Sixty normal adult SD rats aged 9 to 12 weeks were enrolled in this study. Photopic flash ERG were recorded from these 60 SD rats. The results were statistically analyzed with SPSS software. RESULTS: Stable a, b and PhNR wave could be recorded in each rat. Implicit time of a wave, implicit time and amplitude of PhNR fit normal distribution. Implicit time of PhNR was (124.6±8.5) ms with the smallest coefficient of variation of 0.07. The amplitude of PhNR was (11.3±4.2) µV and coefficient of variation was 0.37. There was no difference in the results between female and male rats. CONCLUSION: Photopic flash ERG is an objective method in evaluating the retinal function in SD rats and PhNR can be used as a sensitive index of inner retinal function.