4D traction force microscopy reveals asymmetric cortical forces in migrating Dictyostelium cells.
Phys Rev Lett
; 105(24): 248103, 2010 Dec 10.
Article
em En
| MEDLINE
| ID: mdl-21231559
ABSTRACT
We present a 4D (x; y; z; t) force map of Dictyostelium cells crawling on a soft gel substrate. Vertical forces are of the same order as the tangential ones. The cells pull the substratum upward along the cell, medium, or substratum contact line and push it downward under the cell except for the pseudopods. We demonstrate quantitatively that the variations in the asymmetry in cortical forces correlates with the variations of the direction and speed of cell displacement.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Movimento Celular
/
Microscopia de Força Atômica
/
Dictyostelium
Idioma:
En
Revista:
Phys Rev Lett
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
França