Successful treatment of Old World cutaneous leishmaniasis caused by Leishmania infantum with posaconazole.
Antimicrob Agents Chemother
; 55(4): 1774-6, 2011 Apr.
Article
em En
| MEDLINE
| ID: mdl-21282455
ABSTRACT
Old World cutaneous leishmaniasis is a widespread and potentially disfiguring protozoal infection that is endemic in the Mediterranean basin, Africa, and parts of Asia. Human infection is caused by several species of Leishmania parasites, such as Leishmania infantum. Available systemic and topical treatments vary in efficacy and are often unjustified due to their toxicity. We report on a case that was treated with posaconazole, a drug typically considered an antifungal agent but which also targets specific metabolic pathways of the parasite.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Triazóis
/
Tripanossomicidas
/
Leishmaniose Cutânea
/
Leishmania infantum
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Antimicrob Agents Chemother
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Estados Unidos