[Retrospective study on the prevalence of cardiovascular comorbidities in 4960 inpatients with chronic obstructive pulmonary disease in Beijing].

ABSTRACT

OBJECTIVE: To retrospectively explore the prevalence of cardiovascular disease (CVD) in inpatients with chronic obstructive pulmonary disease (COPD) in Beijing. METHODS: The COPD patients who were discharged from the General Hospital of the Liberation Army, Peking Union medical college Hospital and Beijing Hospital between January 1st, 2000 to March 20th, 2010, were investigated. The prevalence of CVD were calculated. The tendency of the prevalence of CVD by age or discharge year and the difference of the prevalence of CVD between male and female were estimated by using chi-square analysis. RESULTS: There were 4960 COPD patients who were in accordance with the inclusion criteria with 3570 males and 1390 females. The mean age was 72.2 ± 10.4 years. Of the COPD patients, 48.8% were diagnosed as cardiovascular diseases. The age-adjusted over-all prevalence of CVD was 26.4%. Chronic pulmonary heart disease and other disease of pulmonary artery (15.8%) was the most frequent diseases, followed by heart failure (13.6%), ischemic heart disease (10.6%). In COPD patients, male was more likely to have angina, pulmonary heart disease and other disease of pulmonary artery and acute kidney failure (P < 0.05), while less likely to get arrhythmia (atrial fibrillation/atrial flutter), heart failure, pulmonary embolism, hypertension and diabetes mellitus (P < 0.05). The prevalence of arrhythmia increased with age, however, the ischemic heart disease and heart failure decreased. The proportion of CVD decreased in male patients while increased in females. CONCLUSION: The overall prevalence of CVD comorbidities was 48.8% in 4960 patients with COPD who were older than 40 years in Beijing. There were differences among the groups of various age and sex in the distribution of CVD comorbidities frequencies year by year.