Erythrocyte sedimentation rate measurement by VES Matic Cube 80 in relation to inflammation plasma proteins.
J Clin Lab Anal
; 25(3): 198-202, 2011.
Article
em En
| MEDLINE
| ID: mdl-21567468
ABSTRACT
Westergren method is considered as the reference procedure to measure Erythrocyte Sedimentation Rate (ESR) by the International Council for Standardization in Haematology. However, a closed automated method, VES Matic Cube 80 (DIESSE S.p.A., Siena, Italy), has been introduced as a new ESR measurement instrument. In this article, we report two different studies first, we compared the two methods (Westergren and VES Matic Cube 80) and second, we correlated the inflammatory state of 248 patients with their ESR values. Total protein, albumin, C-reactive protein, and other inflammatory proteins were detected in each sample. The results obtained using VES Matic Cube 80 demonstrated a good correlation with those obtained using the Westergren method (Ordinary linear regression y=0.955x-0.205, r(2) =0.816, P<0.05; Passing-Bablock regression equation y=0.9153x-0.5763; Bland-Altman analysis:
bias 1.2; limits of agreement -17.4-19.9) and with the inflammatory protein levels (CRP r=0.554 and r=0.498 and Fibrinogen r=0.699 and r=0.663 for Ves Matic Cube 80 and Westergren, respectively), supporting the hypothesis that VES Matic Cube 80 offers a fast and safe ESR determination, ensuring precision and a very good correlation with the reference method.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas Sanguíneas
/
Testes Hematológicos
/
Inflamação
Limite:
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
J Clin Lab Anal
Assunto da revista:
TECNICAS E PROCEDIMENTOS DE LABORATORIO
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Itália