Early-onset postirradiation sarcoma of the tongue after pseudotumor phase.
ORL J Otorhinolaryngol Relat Spec
; 73(4): 201-5, 2011.
Article
em En
| MEDLINE
| ID: mdl-21701246
ABSTRACT
Radiation-induced sarcoma usually develops after an interval of more than 10 years from the completion of radiation therapy to the diagnosis of secondary sarcoma. However, the theory of radiation-induced transformation does not rule out postirradiation sarcomas with a short latency period. We experienced the case of a patient with postirradiation leiomyosarcoma of the tongue, which occurred 19 months after he had received chemoradiotherapy. Besides the short latency period, a pseudotumor stage developed between the time of radiation exposure and the development of leiomyosarcoma. In this article, we also describe an immunohistochemical approach to diagnose leiomyosarcoma and the efficacy of a gemcitabine and docetaxel regimen.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sarcoma
/
Neoplasias da Língua
/
Granuloma de Células Plasmáticas
/
Neoplasias Induzidas por Radiação
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
ORL J Otorhinolaryngol Relat Spec
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Japão