Highly diastereo- and enantioselective NHC-catalyzed [3+2] annulation of enals and isatins.
Chem Commun (Camb)
; 47(36): 10136-8, 2011 Sep 28.
Article
em En
| MEDLINE
| ID: mdl-21829804
ABSTRACT
The chiral N-heterocyclic carbene bearing a proximal hydroxy group derived from L-pyroglutamic acid was found to be an efficient catalyst for the [3+2] annulation of enals and isatins to give the corresponding spirocyclic oxindolo-γ-butyrolactones in good yield with good diastereo- and enantioselectivities.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Chem Commun (Camb)
Assunto da revista:
QUIMICA
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
China