The 210-kD nuclear envelope polypeptide recognized by human autoantibodies in primary biliary cirrhosis is the major glycoprotein of the nuclear pore.
J Clin Invest
; 86(1): 279-85, 1990 Jul.
Article
em En
| MEDLINE
| ID: mdl-2195063
ABSTRACT
We have recently reported a new family of nuclear autoantibodies in a subset of patients with primary biliary cirrhosis. These antibodies bind to a nuclear envelope polypeptide(s) of approximately 200 kD, the exact identity of which was not established. In this study, we show that all of these autoantibodies are directed against a 210-kD integral membrane glycoprotein of the nuclear pore.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Autoantígenos
/
Glicoproteínas de Membrana
/
Proteínas Nucleares
/
Cirrose Hepática Biliar
/
Membrana Nuclear
Limite:
Humans
Idioma:
En
Revista:
J Clin Invest
Ano de publicação:
1990
Tipo de documento:
Article
País de afiliação:
França