The puzzle of multiple sclerosis: gray matter finds its place.
Expert Rev Neurother
; 11(11): 1565-8, 2011 Nov.
Article
em En
| MEDLINE
| ID: mdl-22014135
ABSTRACT
The way we think of multiple sclerosis (MS) pathology has significantly changed over the last 10 years. Several studies clearly indicate that MS has to be considered a gray and white matter disease, where gray matter pathology probably plays a relevant role in determining physical and cognitive disability. The reviewed article presents new cross-sectional data on gray matter and white matter volumes across different MS phenotypes in a very large group of MS patients. In their study, the authors confirm an early and substantial deterioration of gray matter in MS and the evidence of a primary role of gray matter atrophy in the progression of clinical and cognitive disability. Another preliminary exciting step has therefore been taken toward the comprehension of the MS puzzle.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Expert Rev Neurother
Assunto da revista:
NEUROLOGIA
/
TERAPEUTICA
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Itália