Translocation t(3;22)(q23;q11) in three patients with diffuse large B cell lymphoma.
Leukemia
; 4(5): 373-6, 1990 May.
Article
em En
| MEDLINE
| ID: mdl-2201829
ABSTRACT
In our series of 134 patients with a diagnosis of non-Hodgkin's lymphoma (NHL) and clonal chromosomal abnormalities, three were found to show an identical t(3;22)(q28;q11) translocation. All were old patients with isolated lymphadenomegaly and diffuse large noncleaved cell lymphoma. All expressed a B cell immunophenotype, and all entered a complete remission when treated with aggressive chemotherapy. This translocation could, therefore, delineate a particular subtype of diffuse large cell NHL.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Translocação Genética
/
Cromossomos Humanos Par 3
/
Cromossomos Humanos Par 22
/
Linfoma não Hodgkin
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Leukemia
Assunto da revista:
HEMATOLOGIA
/
NEOPLASIAS
Ano de publicação:
1990
Tipo de documento:
Article
País de afiliação:
França