Type I interferon pathway in adult and juvenile dermatomyositis.
Arthritis Res Ther
; 13(6): 249, 2011.
Article
em En
| MEDLINE
| ID: mdl-22192711
ABSTRACT
Gene expression profiling and protein studies of the type I interferon pathway have revealed important insights into the disease process in adult and juvenile dermatomyositis. The most prominent and consistent feature has been a characteristic whole blood gene signature indicating upregulation of the type I interferon pathway. Upregulation of the type I interferon protein signature has added additional markers of disease activity and insight into the pathogenesis of the disease.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transdução de Sinais
/
Interferon Tipo I
/
Interferon beta
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Interferon-alfa
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Dermatomiosite
Limite:
Adult
/
Child
/
Humans
Idioma:
En
Revista:
Arthritis Res Ther
Assunto da revista:
REUMATOLOGIA
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Estados Unidos