Evaluation of the usefulness of six commercial agglutination assays for serologic diagnosis of toxoplasmosis.
Diagn Microbiol Infect Dis
; 73(3): 231-5, 2012 Jul.
Article
em En
| MEDLINE
| ID: mdl-22541791
ABSTRACT
Six agglutination tests for detecting Toxoplasma gondii-specific antibodies (immunoglobulin G or M) in serum were performed and compared. In total, 599 sera were examined using direct and indirect agglutination assays. Sensitivity varied from 93.7% to 100% and specificity from 97.1% to 99.2%. In a selected population with interfering diseases, the percentage of false positives ranged from 4.3% to 10.9%. Although an overall agreement of 100% was found for chronic toxoplasmosis, sensitivity for the detection of confirmed acute toxoplasmosis ranged from 86.4% to 97.3%. Regarding the large variability in terms of the performance of the 6 assays, tests based on the hemagglutination principle were found to be better than the other agglutination tests for all the panels evaluated, meaning that they could be used as qualitative or semiquantitative low-cost screening assays.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Testes de Aglutinação
/
Toxoplasmose
Tipo de estudo:
Diagnostic_studies
/
Evaluation_studies
/
Qualitative_research
Limite:
Humans
Idioma:
En
Revista:
Diagn Microbiol Infect Dis
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
França