A metabolomic study of preterm human and formula milk by high resolution NMR and GC/MS analysis: preliminary results.
J Matern Fetal Neonatal Med
; 25(Suppl 5): 62-7, 2012 Oct.
Article
em En
| MEDLINE
| ID: mdl-23025771
ABSTRACT
OBJECTIVE:
The aim of the present study was to investigate the metabolic profile of preterm human breast milk (HBM) by using a metabolomic approach.METHODS:
NMR spectroscopy and GC/MS were used to analyze the water-soluble and lipid fractions extracted from milk samples obtained from mothers giving birth at 26-36 weeks of gestation. For the sake of comparison, preterm formula milk was also studied.RESULTS:
The multivariate statistical analysis of the data evidenced biochemical variability both between preterm HBM and commercial milk and within the group of HBM samples.CONCLUSIONS:
The preliminary results of this study suggest that metabolomics may provide a promising tool to study aspects related to the nutrition and health of preterm infant.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Recém-Nascido Prematuro
/
Espectroscopia de Ressonância Magnética
/
Fórmulas Infantis
/
Metabolômica
/
Cromatografia Gasosa-Espectrometria de Massas
/
Leite Humano
Limite:
Humans
/
Newborn
Idioma:
En
Revista:
J Matern Fetal Neonatal Med
Assunto da revista:
OBSTETRICIA
/
PERINATOLOGIA
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Itália