Harnessing the power of the immune system to target cancer.
Annu Rev Med
; 64: 71-90, 2013.
Article
em En
| MEDLINE
| ID: mdl-23092383
ABSTRACT
For many years, immunotherapeutic approaches for cancer held more promise than actual clinical benefit for the majority of patients. However, several recent key advances in tumor immunology have now turned the tide in favor of immunotherapy for the treatment of many different cancer types. In this review, we describe four of the most effective immunotherapeutic approaches currently used in the clinic cancer vaccines, immunostimulatory agents, adoptive T cell therapy, and immune checkpoint blockade. In addition, we discuss some of the most promising future strategies that aim to utilize multiple immunotherapies or combine them with other approaches to more effectively target cancer.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vacinas Anticâncer
/
Sistema Imunitário
/
Imunoterapia
/
Neoplasias
Limite:
Humans
Idioma:
En
Revista:
Annu Rev Med
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Estados Unidos