Impact of Factor V Leiden, prothrombin and methylenetetrahydrofolate reductase gene mutations on infant birth weight in women with recurrent fetal loss and women with successful pregnancies.
Clin Exp Obstet Gynecol
; 39(3): 359-61, 2012.
Article
em En
| MEDLINE
| ID: mdl-23157044
ABSTRACT
PURPOSE:
The aim of this study was to verify whether FV Leiden, PT G20210A, MTHFR C667T or MTHFR A1298C mutations influence the risk of recurrent fetal loss in a sample of Turkish women who had experienced recurrent fetal loss and to evaluate whether the aforementioned thrombophilias and recurrent fetal loss may affect the birth weight of subsequent pregnancies.METHODS:
Fifty-eight women with recurrent pregnancy loss and 30 women with successful pregnancies were evaluated.RESULTS:
The average birth weights for infants of all women in the study group and for infants of thrombophilia-positive women in the study group were markedly lower than the birth weight of infants in the control group (p<0.001 and p<0.001, respectively).CONCLUSION:
Successful pregnancies in women with a history of recurrent fetal losses may be associated with lower birth weights compared to controls, irrespective of thrombophilia status. This conclusion warrants further research.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peso ao Nascer
/
Fator V
/
Protrombina
/
Aborto Habitual
/
Metilenotetra-Hidrofolato Redutase (NADPH2)
/
Mutação
Limite:
Adult
/
Female
/
Humans
/
Pregnancy
País/Região como assunto:
Asia
Idioma:
En
Revista:
Clin Exp Obstet Gynecol
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Turquia