Receptor that can capture a discrete monohydrated fluoride anion.

ABSTRACT

A 'picket calix[4]pyrrole' bearing a well-defined binding domain has allowed the stabilization of a monohydrated fluoride anion. The monohydrated F(-) was observed only when CsF (not the TBAF) was treated with a host in aqueous acetonitrile. The structure of the receptor-bound, monohydrated F(-) was fully characterized by single crystal X-ray diffraction analysis as well as by low temperature (1)H and (19)F NMR spectroscopy. Further analysis revealed that the complex formed a three-dimensional, salt mediated organic framework in the solid state.