Mitochondrial myopathy: a rare cause of early-onset vocal fold atrophy.
Ann Otol Rhinol Laryngol
; 122(3): 177-82, 2013 Mar.
Article
em En
| MEDLINE
| ID: mdl-23577570
ABSTRACT
OBJECTIVES:
We present the second published case of laryngeal involvement in mitochondrial myopathy.METHODS:
A patient with laryngeal involvement of mitochondrial myopathy is presented, together with a literature review.RESULTS:
A 41-year-old man presented with progressive breathy dysphonia. His brother had mitochondrial myopathy. Biopsy of the biceps muscle demonstrated cytochrome C oxidase-negative ragged blue fibers confirming mitochondrial myopathy. Videostroboscopy showed marked vocal fold atrophy, but subsequent injection laryngoplasty did not significantly improve the patient's voice, despite improved postoperative glottic closure.CONCLUSIONS:
Mitochondrial myopathy should be considered in the differential diagnosis of severe early-onset vocal fold atrophy.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Prega Vocal
/
Transtornos de Deglutição
/
Miopatias Mitocondriais
/
Disfonia
/
Músculos Laríngeos
Tipo de estudo:
Etiology_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Ann Otol Rhinol Laryngol
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Estados Unidos