Your browser doesn't support javascript.
loading
Uptake and patterns of use of gemcitabine for metastatic pancreatic cancer: a population-based study.
Oberstein, Paul E; Hershman, Dawn L; Khanna, Lauren G; Chabot, John A; Insel, Beverly J; Neugut, Alfred I.
Afiliação
  • Oberstein PE; Department of Medicine, Columbia University Medical Center, New York, NY 10032, USA.
Cancer Invest ; 31(5): 316-22, 2013 Jun.
Article em En | MEDLINE | ID: mdl-23614655
Gemcitabine was approved for advanced pancreatic cancer in 1996. We investigated uptake and predictors of its use. We identified 3,231 individuals > 65 years in the SEER-Medicare database with stage IV pancreatic adenocarcinoma, diagnosed between 1998-2005, who survived > 30 days. Of these, 54% received chemotherapy, 93% with gemcitabine. Gemcitabine nonreceipt was associated with advanced age and unmarried (OR: 0.65, 95% CI: 0.55-0.76). Diagnosis in 2004-2005 versus 1998-2000 was more likely to receive gemcitabine (OR: 1.51, 95% CI: 1.23-1.84) as were higher SES patients (highest versus lowest quintile, OR: 2.14, 95% CI: 1.60-2.85). Gemcitabine was rapidly adopted among elderly advanced pancreatic cancer patients; several factors are associated with use.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Adenocarcinoma / Desoxicitidina / Antimetabólitos Antineoplásicos Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male País/Região como assunto: America do norte Idioma: En Revista: Cancer Invest Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Adenocarcinoma / Desoxicitidina / Antimetabólitos Antineoplásicos Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male País/Região como assunto: America do norte Idioma: En Revista: Cancer Invest Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Estados Unidos