The (R)-enantiomer of CE3F4 is a preferential inhibitor of human exchange protein directly activated by cyclic AMP isoform 1 (Epac1).
Biochem Biophys Res Commun
; 440(3): 443-8, 2013 Oct 25.
Article
em En
| MEDLINE
| ID: mdl-24099776
Palavras-chave
007; 6-Fluoro-5,7-dibromo-2-methyl-1-formyl-1,2,3,4-tetrahydroquinoline; 8-(4-chloro-phenylthio)-2'-O-methyl-cAMP; CE3F4; CNB; DEP; Disheveled/Egl-10/Pleckstrin; Drug enantiomers; Epac; Epac inhibitor; GEF; PKA; Rap1 GEF; Tetrahydroquinoline analogs; cAMP signaling; cyclic nucleotide binding; exchange protein directly activated by cyclic AMP; guanine-nucleotide exchange factor; protein kinase A
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Quinolinas
/
Fatores de Troca do Nucleotídeo Guanina
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Biochem Biophys Res Commun
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
França