Use of inclusion complex of cyclodextrin with ambenonium to improve the treatment of anticholinesterase poisoning.
Bull Exp Biol Med
; 155(2): 218-20, 2013 Jun.
Article
em En
| MEDLINE
| ID: mdl-24130994
ABSTRACT
The complex of ambenonium with methyl-ß-cyclodextrin injected intramuscularly to rats caused more pronounced inhibition of acetylcholinesterase in erythrocyte and brain than free drug. The use of this complex as part of combined therapy significantly reduces mortality in animals during experimental anticholinesterase poisoning in comparison with the controls.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Acetilcolinesterase
/
Inibidores da Colinesterase
/
Beta-Ciclodextrinas
/
Cloreto de Ambenônio
Limite:
Animals
Idioma:
En
Revista:
Bull Exp Biol Med
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Federação Russa