Tumor-infiltrating follicular helper T cells: The new kids on the block.
Oncoimmunology
; 2(10): e26066, 2013 Oct 01.
Article
em En
| MEDLINE
| ID: mdl-24244900
ABSTRACT
By analyzing CD4+ lymphocytes in human breast carcinomas, we have recently uncovered the presence of follicular helper T cells in lesions exhibiting an extensive immune infiltrate. The presence of these specialized CD4+ T cells, which localize to the germinal centers of peritumoral tertiary lymphoid structures found in extensively infiltrated neoplastic lesions, predicts improved disease outcome among breast carcinoma patients.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
Oncoimmunology
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Bélgica